| 发明名称 |
MODULATION OF NEUROENDOCRINE DIFFERENTIATION BY PROTEIN 25.1 |
| 摘要 |
There is disclosed drug candidate screening assays, diagnostic assays, and therapeutic methods for tumor suppression and the treatment of cancer, including modulating induction of neuroendocrine differentiation in cancer cells, utilizing a novel IGFBP-rP1 interacting protein called P25.1 as the intervention target. The present invention further provides a P25.1 cDNA sequence, a P25.1 polypeptide and fragments thereof, an anti-P25.1 antibody, and anti-25.1 antisense oligonucleotides.
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| 申请公布号 |
CA2389575(A1) |
申请公布日期 |
2001.05.10 |
| 申请号 |
CA20002389575 |
申请日期 |
2000.10.30 |
| 申请人 |
OREGON HEALTH SCIENCES UNIVERSITY |
发明人 |
WILSON, ELIZABETH;OH, YOUNGMAN;ROSENFELD, RON G. |
| 分类号 |
G01N33/50;A61K31/7088;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P11/00;A61P13/08;A61P15/00;A61P15/08;A61P35/00;A61P43/00;C07K14/47;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12Q1/68;C07H21/04;C12N15/11 |
主分类号 |
G01N33/50 |
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