发明名称 |
Polymer stabilized neuropeptides |
摘要 |
A substantially hydrophilic conjugate is provided having a peptide that is capable of passing the blood-brain barrier covalently linked to a water-soluble nonpeptidic polymer such as polyethylene glycol. The conjugate exhibits improved solubility and in vivo stability and is capable of passing the blood-brain barrier of an animal. |
申请公布号 |
AU1631201(A) |
申请公布日期 |
2001.05.10 |
申请号 |
AU20010016312 |
申请日期 |
2000.10.04 |
申请人 |
SHEARWATER CORPORATION |
发明人 |
MICHAEL DAVID BENTLEY;MICHAEL JAMES ROBERTS |
分类号 |
A61K47/32;A61K31/704;A61K38/00;A61K38/22;A61K47/48;A61K49/04;A61P25/04 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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