发明名称 INDOLE COMPOUND AND ITS PHARMACEUTICAL USE
摘要 PROBLEM TO BE SOLVED: To obtain an indole compound selectively acting on estrogen receptorβand useful as a therapeutic medicine for osteoporosis free from adverse effect. SOLUTION: This indole compound is represented by general formula (1) [wherein R1 is hydrogen atom, a lower alkyl group or the like; R5 and R6 may be the same as or different from each other and each represent hydrogen atom, a halogen atom, hydroxy group, a lower alkyl group, a lower alkoxy group or the like; R7 is hydrogen atom, a halogen atom, a lower alkyl group or the like; A, B, D, E and F are each the same or different and denote each =N-, =CH- or the like and Y is phenyl group or the like] or its pharmaceutically permissible salt.
申请公布号 JP2001122855(A) 申请公布日期 2001.05.08
申请号 JP19990305996 申请日期 1999.10.27
申请人 JAPAN TOBACCO INC 发明人 KATO SUSUMU;HAYAKAWA KAZUHIDE;FUJII AKIHIKO
分类号 C07D401/04;A61K31/403;A61K31/404;A61K31/4155;A61K31/4178;A61K31/427;A61K31/437;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61P5/30;A61P5/32;A61P19/10;A61P43/00;C07D209/12;C07D403/04;C07D405/04;C07D409/04;C07D417/04;C07D471/04;(IPC1-7):C07D209/12 主分类号 C07D401/04
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