| 摘要 |
A device for bone tissue engineering is described which comprises a scaffold material consisting of a bioactive, osteoconductive and bone-bonding segmented thermoplastic copolyester and cultured osteogenic or osteoprogenitor cells, especially bone cells. The copolyester consists essentially of a multiplicity of recurring long-chain ester units and short-chain ester units, the long-chain ester units comprising from 35 to 80% by weight of the copolyester and being represented by the formulaand the short-chain ester units being represented by the formulawhereinL is a divalent group remaining after removal of terminal hydroxyl groups from a poly(oxyalkylene) glycol with an average molecular weight of between 300 and 3000;R is a divalent group remaining after removal of carboxyl groups from a dicarboxylic acid having a molecular weight of less than 300;Q is an alkylene group having 1-6 carbon atoms and/or a cyclohexylene of phenylene group; andE is an alkylene group having 2-6 carbon atoms.
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