发明名称 |
Diagnostic assays and kits for body mass and cardiovascular disorders |
摘要 |
The present invention is based at least in part on the discovery of the genomic structure of the human SR-BI gene and on the identification of polymorphic regions within the gene. Accordingly, the invention provides nucleic acids having a nucleotide sequence of an allelic variant of an SR-BI gene and nucleic acids having an SR-BI intronic sequence. The invention also provides methods for identifying specific alleles of polymorphic regions of an SR-BI gene, methods for determining whether a subject has or is at risk of developing a disease which is associated with a specific allele of a polymorphic region of an SR-BI gene, and kits for performing such methods.
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申请公布号 |
US6228581(B1) |
申请公布日期 |
2001.05.08 |
申请号 |
US19980031626 |
申请日期 |
1998.02.27 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;TRUSTEES OF TUFTS COLLEGE |
发明人 |
ACTON SUSAN L.;ORDOVAS JOSE M. |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C02F1/40;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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