发明名称 |
Endothelial monocyte activating polypeptide II: a mediator which activates host response |
摘要 |
This invention provides a purified endothelial monocyte activating polypeptide (EMAP II). It further provides a method of obtaining purified endothelial monocyte activating polypeptide (EMAP II), a method of making antibodies to it and a method of detecting it. This invention also provides an effector cell activating protein which contains an amino acid sequence homologous to RIGRIVT and a method of detecting same. This invention also provides a method of treating a tumor in a subject by administering an effective dose of endothelial monocyte activating polypeptide (EMAP II).
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申请公布号 |
US6228837(B1) |
申请公布日期 |
2001.05.08 |
申请号 |
US19960360821 |
申请日期 |
1996.10.08 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
STERN DAVID M.;CLAUSS MATTHIAS;KAO JANET;KAYTON MARK;LIBUTTI STEVEN K. |
分类号 |
G01N33/53;A61K38/00;A61K39/395;A61P35/00;A61P43/00;C07H21/04;C07K14/52;C07K16/24;C12N15/09;C12P21/02;C12P21/08;(IPC1-7):A61K38/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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