发明名称 |
CONTROLLED-RELEASE BIOCOMPATIBLE OCULAR DRUG DELIVERY IMPLANT DEVICES AND METHODS |
摘要 |
Controlled release devices are disclosed which are biocompatible and can be implanted into the eye. The devices have a core comprising a drug and a polymeric outer layer which is substantially impermeable to the entrance of an environmental fluid and substantially impermeable to the release of the drug during a delivery period, and drug release is affected through an orifice in the outer layer. These devices have an orifice area of less than 10 % of the total surface area of the device and can be used to deliver a variety of drugs with varying degrees of solubility and or molecular weight. Methods are also provided for using these drugs delivery devices.
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申请公布号 |
CA2544460(A1) |
申请公布日期 |
2001.05.03 |
申请号 |
CA20002544460 |
申请日期 |
2000.10.19 |
申请人 |
ALLERGAN SALES, INC. |
发明人 |
BERGER, DONALD E., JR.;HU, MAE W. L.;WONG, VERNON G. |
分类号 |
A61K31/522;A61F2/14 |
主分类号 |
A61K31/522 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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