发明名称 |
PORCINE B7-1 AND ANTIBODIES THERETO |
摘要 |
Soluble and transmembrane porcine B7-1 proteins, their amino acid sequences, nucleic acid sequences coding therefor, as well as antibodies reactive with the B7-1 proteins are disclosed. Methods of making the soluable and transmembrane porcine B7-1 DNA, cDNA, proteins, and antibodies, as well as, methods of using the B7-1 molecules and antibodies thereto, including use in the prevention and/or treatment of rejection of xenotransplants and treatmen t of inflammatory diseases, are described.
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申请公布号 |
CA2361637(A1) |
申请公布日期 |
2001.05.03 |
申请号 |
CA20002361637 |
申请日期 |
2000.10.21 |
申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
ROTHER, RUSSELL P.;FODOR, WILLIAM L.;MATIS, LOUIS A.;FAAS KNIGHT, SUSAN |
分类号 |
A61K38/00;C07K14/705;C07K16/28;(IPC1-7):A61K38/22;C12N15/85;C12N15/70;C12N15/63;A61K39/395;C07H21/04;A61K47/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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