| 摘要 |
<p>[Object] To provide compositions which have a steroid C17,20 lyase inhibitory activity and are useful as preventives and/or remedies for tumors such as prostatism and mammary cancer. Compounds represented by general formula (I) or salts thereof have a steroid C17,20 lyase inhibitory activity and are useful as preventives and/or remedies for tumors such as prostatism and mammary cancer. In said formula R represents hydrogen or a protective group; R1 represents lower alkyl or cyclic hydrocarbyl; R2 represents optionally substituted aryl or optionally substituted heteroaryl; R3 represents optionally substituted hydrocarbyl, optionally substituted hydroxy, optionally substituted thiol, optionally substituted amino, acyl or halogeno; and n is an integer of from 0 to 4.</p> |
