摘要 |
Disclosed are molecules which are not antibodies which bind to the CD40 antigen but which do not cause proliferation, differentiation or activation of B lymphocytes or other cells carrying the CD40 antigen and can inhibit CD40 ligand induced activation. These molecules target, bind to or interact with a particular epitope on CD40. They are useful for treating autoimmune, cell-mediated and antibody-mediated diseases.
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