发明名称 RUTHENIUM (II) COMPLEXES WITH HIGH ANTITUMORAL AND ANTIMETASTATIC ACTIVITIES
摘要 The present invention is related to Ruthenium derived antitumoral compounds with high antimetastatic activity and with low toxicity for the host. It is described the use of inorganic Ruthenium complexes in the therapy of solid tumors, in particular of those tumors characterized by high metastatizing ability. Pharmaceutical compositions containing Ruthenium complexes in formulations suitable for the administration and a kit for the preparation of such complexes at the moment of use or immediately before use, are moreover described.
申请公布号 WO0130789(A1) 申请公布日期 2001.05.03
申请号 WO2000EP10566 申请日期 2000.10.26
申请人 SIGEA S.R.L.;MESTRONI, GIOVANNI;ALESSIO, ENZO;SAVA, GIANNI;IENGO, ELISABETTA;ZORZET, SONIA;BERGAMO, ALBERTA 发明人 MESTRONI, GIOVANNI;ALESSIO, ENZO;SAVA, GIANNI;IENGO, ELISABETTA;ZORZET, SONIA;BERGAMO, ALBERTA
分类号 A61K9/06;A61K9/08;A61K9/10;A61K9/20;A61K9/48;A61K31/7135;A61K45/00;A61K47/20;A61K47/22;A61K47/34;A61P35/00;A61P35/04;A61P43/00;C07C317/04;C07F15/00;(IPC1-7):C07F15/00 主分类号 A61K9/06
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