A PROCESS FOR MANUFACTURE OF HYDROGELS FOR BURN AND INJURY TREATMENT

摘要

In this invention a process for manufacture of hydrogel dressing by cross-linking aqueous solution of synthetic polymer namely poly vinyl alcohol (PVA) and natural polymer agar-agar and one or more of other natural polymers from carageenan, sodium alginate and sodium carboxymethyl cellulose, gum acacia or similar polysaccharides or protein like gelatine etc. by gamma or electron beam irradiation has been described. In the process the ingredients are dissolved in distilled/deionized water at elevated temperatures. The hot solution is poured in disposable plastic mould, closed tightly and subjected to radiation dose between 25 to 60 kGy to give final, ready to use, high water content, transparent, flexible, self adhesive gel dressing. The pre irradiated gel solution contains 5-15 % by weight of PVA, 0.5 to 5 % by weight of natural polymers and distilled water not less than 80 % by weight.