| 摘要 |
The invention discloses an allele of an apolipoprotein E (Apo-E) gene, or an expression product of said allele, which correlate with the development and/or progression of a neuropsychiatric disorder associated with interferon treatment. Also disclosed are methods for diagnosis of a predisposition to the development and/or progression of a neuropsychiatric disorder associated with interferon treatment by detecting the presence of an allele of an Apo-E gene, or an expression product thereof, which correlate with that predisposition. The invention also discloses a method of treatment of a disease or condition based on said diagnosis. |
