发明名称 |
Fremgangsmåte for fremstilling av suspensjoner av legemiddelpartikler for inhalering |
摘要 |
<p>The invention is directed to a process for the preparation of suspensions of drug particles for inhalation delivery, said process providing particles of optimised particle size and distribution homogeneously dispersed in the carrier. The process, which is also suitable for the preparation of sterile suspensions, includes the step of homogenising and micronising the formulation in a turboemulsifier provided with a high-potency turbine, optionally followed by a treatment in a high-pressure homogeniser. A further aspect of the invention is directed to a process for preparing micronised sterile beclomethasone dipropionate by gamma-irradiation.</p> |
申请公布号 |
NO20012175(D0) |
申请公布日期 |
2001.05.02 |
申请号 |
NO20010002175 |
申请日期 |
2001.05.02 |
申请人 |
CHIESI FARMACEUTICI SPA |
发明人 |
BERNINI, EVA;CARZIA, RAFFAELLA;CHIESI, PAOLO;MALVOLTI, CHIARA;BRAMBILLA, GAETANO |
分类号 |
A61L2/08;A61K;A61K9/00;A61K9/10;A61K9/12;A61K9/72;A61K31/56;A61K31/573;A61P;A61P11/00;A61P37/00;(IPC1-7):A61K |
主分类号 |
A61L2/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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