发明名称 |
Substituted urea and isothiorea derivatives as no synthase inhibitors |
摘要 |
The use of an N-substituted urea derivative for the manufacture of a medicament for the treatment of a condition where there is an advantage in inhibiting the NO synthase enzyme, in particular cerebral ischemia, and pharmaceutical formulations therefor are disclosed. Novel N-substituted urea derivatives and processes for the preparation thereof are also described.
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申请公布号 |
US6225305(B1) |
申请公布日期 |
2001.05.01 |
申请号 |
US20000514525 |
申请日期 |
2000.02.28 |
申请人 |
GLAXO WELLCOME INC. |
发明人 |
OPLINGER JEFFREY ALAN;SHEARER BARRY GEORGE;BIGHAM ERIC CLEVELAND;FURFINE ERIC STEVEN;GARVEY EDWARD PATRICK |
分类号 |
A61K31/00;A61K31/135;A61K31/155;A61K31/195;A61K31/425;A61K31/44;C07C275/70;C07C335/32;C07D213/75;C07D277/18;(IPC1-7):A61K31/44;A61K31/395;A61K31/215 |
主分类号 |
A61K31/00 |
代理机构 |
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地址 |
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