| 发明名称 |
SITE SPECIFIC MUTAGENESIS IN ALPHA-1-ANTITRYPSIN |
| 摘要 |
Methods are provided for producing sites specific mutagenized alpha-1-antitrypsin. Particular mutants are formed having a mutation in the active site of alpha-1- antitrypsin at amino acid position 358 and at amino acid position 342.
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| 申请公布号 |
CA1341219(C) |
申请公布日期 |
2001.05.01 |
| 申请号 |
CA19850476337 |
申请日期 |
1985.03.13 |
| 申请人 |
ZYMOGENETICS, INC. |
发明人 |
INSLEY, MARGARET Y;KAWASAKI, GLENN HITOSHI |
| 分类号 |
A61K35/74;A61K38/00;A61K38/16;A61K38/55;A61P7/02;A61P43/00;C07H21/04;C07K14/005;C07K14/195;C07K14/81;C12N9/99;C12N15/00;C12N15/09;C12N15/10;C12N15/15;C12N15/81;C12P21/02;C12R1/865;(IPC1-7):C12N15/15;C12N1/16;C12N1/20;C12N15/63;C12N15/70 |
主分类号 |
A61K35/74 |
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