发明名称 Amidino protease inhibitors
摘要 Amidino and benzamidino compounds, including compounds of the formula:wherein R1-R4, R6-R9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula I.
申请公布号 US6225302(B1) 申请公布日期 2001.05.01
申请号 US20000631107 申请日期 2000.08.01
申请人 3-DIMENSIONAL PHARMACEUTICALS, INC. 发明人 LU TIANBAO;TOMCZUK BRUCE E.;ILLIG CARL R.;SOLL RICHARD M.
分类号 C07D295/14;A61K31/00;A61K31/18;A61K31/24;A61K31/445;A61K31/495;A61P1/00;A61P1/18;A61P7/00;A61P7/02;A61P9/00;A61P9/10;A61P29/00;A61P43/00;C07C309/73;C07C311/21;C07D211/22;C07D211/26;C07D211/28;C07D295/195;(IPC1-7):A61K31/445;C07D211/62 主分类号 C07D295/14
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