发明名称 Use of alkylated iminosugars to treat multidrug resistance
摘要 Methods and compositions for preventing, reducing, or reversing multidrug resistance (MDR) during cancer chemotherapy in patients undergoing treatment with therapeutically effective amounts of chemotherapeutic agents are provided. The methods comprise administering an anti-MDR effective amount of an N-substituted-1,5-dideoxy-1,5-imino-D-glucitol or galactitol iminosugar to a patient.
申请公布号 US6225325(B1) 申请公布日期 2001.05.01
申请号 US19980189177 申请日期 1998.11.10
申请人 G.D. SEARLE & COMPANY 发明人 JACOB GARY S.
分类号 A61K31/445;A61K31/475;A61K38/08;A61K45/06;A61P35/00;A61P43/00;C07D211/46;(IPC1-7):A01N43/40 主分类号 A61K31/445
代理机构 代理人
主权项
地址