摘要 |
A sustained and controlled release form of iodine is achieved by a complex of polyvinyl alcohol starch and iodine, characterized by the PVA based coating being insoluble in boiling water. The polyvinyl alcohol is in the form of a coating reacted with varying types of non-mineral acid containing catalysts/curing or insolubilizing agents deposited on cellulose sponge or other substrates and subsequently complexed with iodine. These cost effective sponges or wipers are topically applied as a solid state antimicrobial device, which releases controlled amounts of iodine on contact sufficient to kill germ cells, and leaves minimal residue. |