| 发明名称 |
CONJUGATES PRODUCED FROM METAL AND OLIGONUCLEOTIDE COMPLEXES, MEANS CONTAINING THE CONJUGATES, METHOD FOR PRODUCING AND USING THE CONJUGATES IN RADIOLOGICAL DIAGNOSIS |
| 摘要 |
biochemistry. SUBSTANCE: oligonucleotides are modified for hindering or at least essentially inhibiting their degradation with nucleases occurring in nature. Oligonucleotide radical is specifically bound with high binding affinity to target structures and produces in this manner specific therapeutic and diagnostic action by means of bound complex-generating agent or complex. EFFECT: wider number of preparation for diagnosing pathologic states. 17 cl, 3 dwg
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| 申请公布号 |
RU2165771(C2) |
申请公布日期 |
2001.04.27 |
| 申请号 |
RU19970102039 |
申请日期 |
1995.06.30 |
| 申请人 |
SHERING AG;NEKSTAR FARMAS'JUTIKALZ, INK. |
发明人 |
LUDGER DINKEL'BORG;KRISTOF-SHTEFAN KHIL'GER;UL'RIKH NIDBALLA;JOKHANNES PLATTSEK;BERND RADJUKHEL';UL'RIKH SHPEK;LARRI GOLD;VOL'FGANG PIKEN |
| 分类号 |
C12N15/09;A61K31/70;A61K31/7135;A61K41/00;A61K51/00;A61K51/04;A61P35/00;C07H21/00;C07H23/00;C12Q1/68;(IPC1-7):A61K41/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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| 地址 |
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