ANALOGUES OF VITAMIN D, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION

摘要

organic chemistry, vitamins, steroids. SUBSTANCE: invention relates to synthetic derivatives of vitamin D of the general formula (I) where Q means CH2- or -C=C- and -C1-C6-alkylene; R1 means H, C1-C4-alkyl; group YR1 where Y means -SO-, C1-C4-alkyl; Z means H or hydroxyl. Compounds show anti-inflammatory and immunomodulating effect and strong activity stimulating differentiation and inhibiting nondesirable proliferation of some cells also. EFFECT: improved method of synthesis, valuable medicinal properties. 8 cl, 26 ex