| 发明名称 |
ALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE |
| 摘要 |
Alkylamino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives of formula (I) are provided wherein R<1>-R<3> are as defined in the application which are useful as inhibitors of p38, along with a process for their manufacture and pharmaceutical preparations containing them.
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| 申请公布号 |
WO0129041(A1) |
申请公布日期 |
2001.04.26 |
| 申请号 |
WO2000EP10077 |
申请日期 |
2000.10.13 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
DUNN, JAMES, PATRICK;GOLDSTEIN, DAVID, MICHAEL;HARRIS, WILLIAM;SMITH, IAN, EDWARD, DAVID;WELCH, TERESA, ROSANNE |
| 分类号 |
A61K31/519;A61P1/00;A61P1/04;A61P9/10;A61P11/00;A61P11/06;A61P17/04;A61P19/02;A61P29/00;A61P43/00;C07D487/04;(IPC1-7):C07D487/04;A61K31/505 |
主分类号 |
A61K31/519 |
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