发明名称 |
COMPOSITIONS, KITS, AND METHODS FOR MODULATING SURVIVAL AND DIFFERENTIATION OF MULTI-POTENTIAL HEMATOPOIETIC PROGENITOR CELLS |
摘要 |
The invention includes compositions, kits, and methods for modulating survival and differentiation of mammalian multi-potential hematopoietic progenitor cells using a placental glycoprotein hormone of the murine prolactin family, namely either murine prolactin-like protein E or murine prolactin-like protein F. The compositions, kits, and methods described herein can be used, for example, for <i>in vitro</i> or <i>ex vivo</i> expansion of hematopoietic precursor cells or to treat a disorder associated with aberrant hematopoiesis (e.g., pre-eclampsia and thrombocytopenia).
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申请公布号 |
WO0100788(A3) |
申请公布日期 |
2001.04.26 |
申请号 |
WO2000US17345 |
申请日期 |
2000.06.23 |
申请人 |
NORTHWESTERN UNIVERSITY |
发明人 |
LEFEBVRE, PHIL;LIN, JIANDIE;COHEN, ISAAC;LINZER, DANIEL |
分类号 |
A61K35/12;C12N5/02;C12N5/078;C12N5/0789;(IPC1-7):A01N1/02;C12N5/00;C07K14/52;C07K16/00 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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地址 |
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