The present invention relates to methods for the treatment and diagnosis of immune related diseases, including those mediated by cytokines released primarily either Th1 or Th2 cells in response to antigenic stimulation. The present invention further relates to methods for biasing the differentiation of T-cells in either the Th1 subtype or the Th2 subtype, based on the relative expression levels of the gene TCCR, and its agonists or antagonists. The present invention further relates to a method of diagnosing Th1- and Th2-mediated diseases.
申请公布号
WO0129070(A2)
申请公布日期
2001.04.26
申请号
WO2000US28827
申请日期
2000.10.18
申请人
GENENTECH, INC.;DE SAUVAGE, FREDERIC, J.;GREWAL, IQBAL;GURNEY, AUSTIN, L.
发明人
DE SAUVAGE, FREDERIC, J.;GREWAL, IQBAL;GURNEY, AUSTIN, L.
