发明名称 |
SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES |
摘要 |
The present invention is directed to 9-substituted guanine derivatives in which the guanine moiety is linked to another moiety with physiological or pharmacological activity through a carboxamide linkage. The number of carbon atoms between the guanine moiety and the carboxamide linking group is typically from 1 to 6. In some cases, the chemical moieties can have carbon chains of different lengths within the moiety linked to guanine through the carboxamide linker. A large number of different chemical moieties can be linked to the guanine moiety. The invention also includes pharmaceutical compositions including the 9-substituted guanine derivatives and methods of use of the 9-substituted guanine derivatives.
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申请公布号 |
CA2384789(A1) |
申请公布日期 |
2001.04.26 |
申请号 |
CA20002384789 |
申请日期 |
2000.10.13 |
申请人 |
NEOTHERAPEUTICS, INC. |
发明人 |
GLASKY, ALVIN |
分类号 |
A61K31/522;A61K31/5377;A61K31/708;A61P1/04;A61P3/10;A61P9/06;A61P9/12;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P43/00;C07D473/18;C07D519/00;C07H5/06;(IPC1-7):C07D473/18;A61K31/52 |
主分类号 |
A61K31/522 |
代理机构 |
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主权项 |
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地址 |
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