| 发明名称 |
9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS |
| 摘要 |
The present invention is related to piperazine derivatives of carbazole of formula (I) notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such piperazine derivatives of carbazole. Said piperazine derivatives of carbazole are efficient modulators , in particular efficient inhibitors, of the Bax function and/or activation. T he present invention is furthermore related to novel piperazine derivatives of carbazole as well as methods of their preparation.
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| 申请公布号 |
CA2385456(A1) |
申请公布日期 |
2001.04.26 |
| 申请号 |
CA20002385456 |
申请日期 |
2000.10.18 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
MARTINOU, JEAN-CLAUDE;GERBER, PATRICK;BOMBRUN, AGNES;CHURCH, DENNIS;ANTONSSON, BRUNO;HALAZY, SERGE |
| 分类号 |
C07D401/12;A61K31/495;A61K31/496;A61K31/5377;A61P1/00;A61P1/16;A61P9/00;A61P9/04;A61P9/10;A61P11/06;A61P13/12;A61P15/08;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P37/06;A61P43/00;C07D209/86;C07D209/88;C07D403/06;C07D405/12;C07D407/14;C07D409/04;C07D409/12;C07D413/12;C07D417/12;C07D417/14;(IPC1-7):C07D403/06 |
主分类号 |
C07D401/12 |
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