发明名称 |
IMMUNO-INTERACTIVE FRAGMENTS OF THE .ALPHA.C SUBUNIT OF INHIBIN |
摘要 |
Novel immuno-interactive fragments of the .alpha.C portion of a mammalian inhibin .alpha.-subunit are disclosed, together with their variants and derivatives for producing antigen-binding molecules that are interactive wit h said .alpha.C portion, which are chemically well defined and which can be produced in commercially significant quantities. The antigen-binding molecul es of the invention can be used for the detection of a mammalian inhibin and fo r the treatment and/or prevention of conditions associated with aberrant level s of a mammalian inhibin.
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申请公布号 |
CA2387576(A1) |
申请公布日期 |
2001.04.26 |
申请号 |
CA20002387576 |
申请日期 |
2000.10.18 |
申请人 |
PRINCE HENRY'S INSTITUTE OF MEDICAL RESEARCH |
发明人 |
GROOME, NIGEL PATRICK;STANTON, PETER GORDON;MILNE-ROBERTSON, DAVID MARK;CAHIR, NICHOLAS FRANCIS |
分类号 |
A61K39/00;A61P5/00;A61P35/00;C07K14/575;C07K16/18;C12N15/12;G01N33/574;G01N33/74;(IPC1-7):C12N15/12;C07K7/08;A61K38/10;A61K38/17;A61K39/395;C07K14/47;G01N33/53 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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