POLYPEPTIDE FRAGMENTS COMPRISING C-TERMINAL PORTION OF <i>HELICOBACTER</i> CATALASE

摘要

An isolated polypeptide and immunogenic fragments thereof are described together with their variants and derivatives as novel immunogenic agents for treating or preventing Helicobacter infection in a mammalian host. The polypeptide comprises a C-terminal portion of a Helicobacter catalase, which portion lacks significant amino acid sequence identity with human catalase, wherein the polypeptide is other than full-length Helicobacter catalase.