发明名称 |
PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS |
摘要 |
Novel cannabimimetic pyrazole derivatives are presented which have preferentially high affinities for both of the cannabinoid CB1 or CB2 recept or sites. The improved receptor affinity makes these analogs useful as experimental tools for cannabinoid receptor studies as well as clinically useful agents in individuals and animals for treatment of memory deficits associated with aging or neurological diseases, as anti-obesity agents, as medications for schizophrenia and treatment of septic shock syndrome.</SDOAB >
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申请公布号 |
CA2387892(A1) |
申请公布日期 |
2001.04.26 |
申请号 |
CA20002387892 |
申请日期 |
2000.10.18 |
申请人 |
UNIVERSITY OF CONNECTICUT |
发明人 |
MAKRIYANNIS, ALEXANDROS;LIU, QIAN |
分类号 |
A61K31/415;A61P1/00;A61P3/04;A61P9/00;A61P9/08;A61P15/18;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P27/06;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P43/00;C07D231/14;(IPC1-7):C07D231/14 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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