N-SUBSTITUTED 3-AMINO-2,2-DI-C-ALKYL-1,4-BUTYROLACTONES AND 1,4-THIOBUTYROLACTONES FOR USE AS PROMOTER OF η-AMINOBUTYRIC ACID ACTIVITY AND FOR TREATING NERVOUS DISORDERS AND PREPARATION METHOD

摘要

The invention concerns compounds represented by general formula (I) wherein: Z represents a sulphur or oxygen atom; the groups R1 and R2, identical or different, represent each an alkyl group or an alkenyl group; X represents a CO, a CO2, an SO or and SO2 and the group R represents an alkyl, aryl, alkenyl or aralkyl group, provided that when Z represents an oxygen atom, X an SO2 and R a group (a), R1 and R2 do not both represent the methyl group. The invention also concerns methods for preparing said compounds, pharmaceutical compositions containing them and their use as promoter of η-aminobutyric acid and as medicine particularly designed for treating nervous disorders.