发明名称 Pyridyl-and pyrimidyl-piperazines in the treatment of substance abuse disorders
摘要 Use of a compound of formula (I) and the pharmaceutically acceptable acid addition salts thereof, wherein R1 is either halogen or hydrogen and R2 is halogen; X is CH2, O or S; R3 and R4 are the same or different and selected from hydrogen or lower alkyl; n is 2 or 3; A is selected from the pyrimidyl- or pyridyl-groups (a), (b) or (c) wherein R5, R6 and R7 are as defined in the description; for the manufacture of a medicament for the relief or prevention of a withdrawal syndrome resulting from addiction to a drug or substance of abuse or for treatment thereof.
申请公布号 US6221858(B1) 申请公布日期 2001.04.24
申请号 US19980180292 申请日期 1998.11.05
申请人 PHARMACIA & UPJOHN AB 发明人 BJOERK ANDERS
分类号 C07D213/38;A61K31/00;A61K31/495;A61K31/496;A61K31/505;A61K31/506;A61K31/535;A61K31/5375;A61K31/5377;A61P25/30;A61P25/34;A61P25/36;(IPC1-7):C07D401/04;C07D401/14;C07D403/04;C07D413/14 主分类号 C07D213/38
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