Process for preparing optically pure(S)-3,4-dihydroxybutyric acid derivatives

摘要

The present invention relates to a process for preparing optically pure (S)-3,4-dihydroxybutyric acid derivatives expressed by the following Formula 1 and more particularly, to a process that enables preparing optically pure (S)-3,4-dihydroxybutyric acid derivatives economically in large quantities, by:(a) Preparing alpha-(1,4)-linked oligosaccharide with adequate sugar distribution by reacting amylopectin which is easily available from natural product with enzyme under a specific condition; and(b) Performing oxidation and esterification sequentially under a specific condition.wherein, R represents linear or branched alkyl group with 1~5 carbon atoms.