发明名称 |
Anti-pathogen system and methods of use thereof |
摘要 |
The present invention provides an anti-pathogen system comprising one or more fusion proteins that includes a transduction domain and a cytotoxic domain. The cytotoxic domain is specifically activated by a pathogen infection. The anti-pathogen system effectively kills or injures cells infected by one or a combination of different pathogens. Further provided are protein transduction domains that provide enhanced transduction efficiency.
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申请公布号 |
US6221355(B1) |
申请公布日期 |
2001.04.24 |
申请号 |
US19980208966 |
申请日期 |
1998.12.10 |
申请人 |
WASHINGTON UNIVERSITY |
发明人 |
DOWDY STEVEN F. |
分类号 |
G01N33/53;A61K38/00;A61K38/43;A61K39/00;A61K45/08;A61P39/00;C07K14/16;C07K19/00;C12N9/12;C12N9/50;C12N9/64;C12N15/09;C12P21/08;C12Q1/68;(IPC1-7):A61K39/00;A61K39/12;A61K39/21;C07H21/04 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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