| 发明名称 |
Monoclonal antibodies specific for human thymidylate synthase |
| 摘要 |
The present invention relates to monoclonal antibodies that are specific for the protein thymidylate synthase, and hybridomas producing these monoclonal antibodies. The invention further relates to methods of detection and diagnostic kits to test for the presence of thymidylate synthase. The invention also relates to the use of the monoclonal antibodies in determining the presence of colon carcinoma cells.
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| 申请公布号 |
US6221620(B1) |
申请公布日期 |
2001.04.24 |
| 申请号 |
US19910690841 |
申请日期 |
1991.04.24 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
JOHNSTON PATRICK G.;ALLEGRA CARMEN J.;CHABNER BRUCE A.;LIANG CHI-MING |
| 分类号 |
C12N5/10;C07K16/30;C07K16/40;C12N15/02;C12P21/08;C12R1/91;G01N33/53;(IPC1-7):C07K1/00;C07H21/02 |
主分类号 |
C12N5/10 |
| 代理机构 |
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