发明名称 |
Beta-lactam inhibitors of CoA-IT |
摘要 |
This invention relates to methods for treating diseases or disorders mediated by lipid inflammatory mediators, arachidonic acid, its metabolites and/or platelet activating factor (PAF), which method comprises administration to a mammal in need thereof of an effective Coenzyme A independent transacylase (CoA-IT) inhibiting amount of a triphenylmethylazetidinone. This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a triphenylmethylazetidinone.
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申请公布号 |
US6221860(B1) |
申请公布日期 |
2001.04.24 |
申请号 |
US19990423421 |
申请日期 |
1999.11.08 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
BONDINELL WILLIAM E.;WINKLER JAMES DAVID |
分类号 |
A61K31/397;A61K31/4427;(IPC1-7):A01N43/00;A01K31/395 |
主分类号 |
A61K31/397 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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