| 摘要 |
Novel nitrosourea derivatives are provided which possess a high level of inhibitory activity against leukemia and tumors and other are therefore useful for pharmaceutical purposes. The compounds have the structure: <IMAGE> (I) wherein one of X and Y represents a hydroxyl and another of them represents a group -NHCONNOCH2CH2Cl; R represents a hydrogen, alkyl or aryl; and DIFFERENCE represents a single bond which may be in the alpha - or beta -stereochemical configuration and are prepared by nitrosating a corresponding urea compound with a nitrosating agent in a manner known per se.
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