发明名称 |
Methods to identify compounds that modulate neuronal activity |
摘要 |
A specific amino acid sequence proximal to the carboxy terminus of P/Q type ion channels has been shown to mediate, through binding to the Homer protein, the expression of the gene encoding syntaxin-1A. This region of the P/Q type calcium ion channel provides peptides that can be used in screening assays for compounds that modulate the central nervous system. |
申请公布号 |
AU7896700(A) |
申请公布日期 |
2001.04.23 |
申请号 |
AU20000078967 |
申请日期 |
2000.10.13 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
TERRANCE P. SNUTCH |
分类号 |
G01N33/50;A61K45/00;A61P25/28;C07K14/47;C07K16/18;C12N1/16;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;G01N33/15;G01N33/53;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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