| 摘要 |
organic synthesis. SUBSTANCE: invention provides novel phenylacetic acid derivatives of general formula I: (I), in which X denotes NOCH3, CHOCH3 and CHCH2CH3; R1 hydrogen or C1-C4-alkyl; R2 halogen, C1-C4-alkyl, or C1- C4-alkoxy; m= 0 or 1; R3 denotes hydrogen, amino, halogen, C1-C4-alkyl, C1- C4-haloalkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-alkylamino, or di- C1- C4-alkylamino; R4 cyano, halogen, C1-C6-alkyl, C1-C6-alkoxy, C2-C6- alkenyl, C2-C6-alkenyloxy, or C2-C6-alkinyl; provided that hydrocarbon moieties of above-indicated groups can be partially or completely halogenated or can bear one to three substituents selected from cyano, C1- C6-alkoxy, C1-C6-alkoxycarbonyl, phenyl, and dioxan (cyclic radicals can be partially or completely halogenated), C3-C6-cycloalkyl, C3-C6-cycloalkenyl, aryl, isoxazolyl, pyridyl, dioxolanyl, benzoxazolyl, thienyl, oxazolyl, furyl, oxyranyl, pyrazolyl, thiazolyl, pyrimidyloxy or tetrahydropyranyl, provided that cyclic radicals can be partially or completely halogenated or can bear one to three substituents selected from nitro, C1-C6-alkyl, C1-C6- alkoxy, C1-C6-haloalkyl, C1-C6-alkylamino, di-C1-C6-alkylamino and aryl; R5 denotes hydrogen, C1-C10-alkyl, C2-C10-alkenyl, or C2-C10-alkinyl, provided that these radicals can be partially or completely halogenated or can bear one to three substituents selected from cyano, hydroxy, aminocarbonyl, C1-C6-alkyl, C2-C6-alkenyl, C1-C6-alkoxycarbonyl, C1-C6- alkylamino, benzyl, aryl, aryloxy, thienyl, pyrrolyl, oxazolyl, furyl, thiazolyl, oxadiazolyl, and isoxazolyl, cyclic radicals themselves can be partially or completely halogenated or can bear one to three substituents selected from nitro, hydroxy, C1-C4-alkyl, C1-C4-haloakyl, and C3-C6- cycloalkyl; on condition that X cannot be NOCH3 and CHOCH3, when R4 is unsubstituted C1-C4-alkyl, unsubstituted C3-C6-cycloalkyl, substituted or unsubstituted phenyl, or unsubstituted thienyl; or X cannot be CHOCH3, when R3 is hydrogen and R5 is C1-C10-alkyl; as well as salts or above-indicated compounds. Compound I show fungicidal activity. EFFECT: extended choice of active fungicides. 8 cl, 16 tbl, 10 ex |
