| 摘要 |
synthesis of biologically-active compounds. SUBSTANCE: invention provides novel derivatives of indolylalkyl-pyrimidinyl-piperazines having general formula I , in which R1, R2, R3 and R5 are hydrogen atoms; R4 is lower alkoxy; R6 amino, lower alkylamino, di-loweralkylamino, or lower alkoxy; X is selected from S, SO, and SO2; Y and Z are nitrogen atoms; m=0,1,2, or 3; and n is integer from 1 to 5. Compounds may be utilized to alleviate vascular-origin headaches. EFFECT: increased choice of vasodilators. 9 cl, 3 dwg, 14 ex |
