发明名称 PYRIMIDINE DERIVATIVES
摘要 The invention concerns pyrimidine derivatives of Formula (I) wherein m is 0-3 and each R<1> is a group such as hydroxy, halogeno, trifluoromethyl and cyano; R<3> is hydrogen, halogeno or (1-6C)alkyl; n is 0-2 and each R<2> is a group such as hydroxy, halogeno, trifluoromethyl and cyano; p is 0-4; and Q<1> is aryl or heteroaryl; or pharmaceutically acceptable salts or in vivo cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
申请公布号 WO0127089(A1) 申请公布日期 2001.04.19
申请号 WO2000GB03929 申请日期 2000.10.10
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;CUMMING, JOHN, GRAHAM 发明人 CUMMING, JOHN, GRAHAM
分类号 A61K31/505;A61K31/506;A61K31/5377;A61K31/541;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P3/14;A61P7/00;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P19/04;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P35/04;A61P37/08;A61P39/02;A61P43/00;C07D239/42;C07D239/46;C07D239/47;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D413/14;C07D417/12;C07D417/14;(IPC1-7):C07D239/42 主分类号 A61K31/505
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