INHIBITORS OF FACTOR XA HAVING AN ARGININE OR ARGININE ALDEHYDE MIMIC
摘要
Peptidyl aldehydes having an arginine or arginine mimic at P3 which are selective inhibitors of certain serine proteases, including factor Xa, are described. These compounds are useful in prevention and treatment of conditions characterized by abnormal thrombosis in mammals.
申请公布号
WO0127141(A1)
申请公布日期
2001.04.19
申请号
WO2000US27615
申请日期
2000.10.06
申请人
CORVAS INTERNATIONAL, INC.
发明人
SEMPLE, JOSEPH, EDWARD;BRUNCK, TERENCE, KEVIN;LEVY, ODILE, ESTHER;TAMURA, SUSAN, Y.
