| 摘要 |
Caspase-3 inhibiting compounds of formula (I): as well as pharmaceutical compositions and methods of treatment are disclosed. The compounds are usefu l for treating caspase-3 mediated diseases and conditions, among which are cardiac or cerebral ischemia or reperfusion injury, type I diabetes, immune deficiency syndrome, includings AIDS, cerebral and spinal cord trauma injury , organ damage during transplantation, alopecia, aging, Parkinson's disease, Alzheimer's disease, Down's syndrome, spinal muscular atrophy, multiple sclerosis and neurodegenerative disorders.
|
