发明名称 Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
摘要 A pharmaceutical composition incorporates a pharmaceutically effective amount of at least two components, one of those components being a nicotinic compound capable of interacting with nicotinic cholinergic receptors (e.g., a nicotinic agonist, such as E-metanicotine) and one of those components being an acetylcholinesterase inhibitor (e.g., tacrine). The pharmaceutical composition is useful for treating CNS disorders, such as Alzheimer's disease.
申请公布号 US6218383(B1) 申请公布日期 2001.04.17
申请号 US19980130498 申请日期 1998.08.07
申请人 TARGACEPT, INC. 发明人 BENCHERIF MEROUANE
分类号 A61K45/06;A61K31/4375;A61K31/44;A61K31/465;A61K31/55;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28;(IPC1-7):A61K31/55 主分类号 A61K45/06
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