发明名称 |
Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
摘要 |
Hybridoma cell lines producing monoclonal antibodies specific to the human epidermal growth factor receptor are disclosed. The antibodies are capable of inhibiting the growth of human tumor cells expressing human epidermal growth factor receptors. Therapeutic uses of these monoclonal antibodies by themselves and in combination with anti-neoplastic agents are also disclosed.
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申请公布号 |
US6217866(B1) |
申请公布日期 |
2001.04.17 |
申请号 |
US19950487761 |
申请日期 |
1995.06.07 |
申请人 |
RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. |
发明人 |
SCHLESSINGER JOSEPH;GIVOL DAVID;BELLOT FRANCOISE;KRIS RICHARD;RICCA GEORGE A.;CHEADLE CHRISTOPHER;SOUTH VICTORIA J. |
分类号 |
A61K45/00;A61K31/704;A61K33/24;A61K38/00;A61K39/395;A61P35/00;A61P43/00;C07K16/28;C07K16/30;C12P21/08;C12R1/91;(IPC1-7):A61K39/395 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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