| 摘要 |
PROBLEM TO BE SOLVED: To obtain an anti-rotavirus active substance which is derived from a natural product and hardly exhibits adverse drug reactions and to prevent or treat infectious diseases of human infants and infants of animals for industrial use, pets or the like. SOLUTION: The extract from stevia plant bodies, mainly stems and leaves, inhibits the adhesion or invasion of rotavirus into the cell and exhibits resistance to gastric acid. The active ingredient contained in the extract is present in a fraction obtained by eluting the extract with water by the use of ODS column and then eluting the resultant eluate with 20-70% ethanol. The ingredient is an acidic polysaccharide with a molecular weight of 20,000-80,000. |
