发明名称 Compounds and methods for the selective treatment of cancer and bacterial infections
摘要 The present invention relates to compounds containing an anthracyclinone group such as doxorubicin, daunorubicin or a derivative thereof. The compounds of the invention also contain ester, glycoside or glucuronide structures which are hydrolyzed by the corresponding esterase, glycosidase or glucuronidase. These compounds possess potent cytotoxic activity which is developed after the hydrolysis of the ester or glycoside group of the compound and are effective in the inhibition of tumor cells and bacterial growth after activation.
申请公布号 US6218519(B1) 申请公布日期 2001.04.17
申请号 US19960635243 申请日期 1996.04.12
申请人 PRO-NEURON, INC. 发明人 KENTEN JOHN H.;SIMPSON DAVID M.
分类号 C07H15/252;(IPC1-7):C07H15/24 主分类号 C07H15/252
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