| 发明名称 |
G PROTEIN-COUPLED RECEPTOR UP-REGULATED IN PROSTATE CANCER AND USES THEREOF |
| 摘要 |
A novel gene (designated PHOR-1) that is highly over-expressed in prostate a nd other cancers and its encoded protein are described. PHOR-1 is a G protein- coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over - expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/o r therapeutic target for prostate cancer.
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| 申请公布号 |
CA2385032(A1) |
申请公布日期 |
2001.04.12 |
| 申请号 |
CA20002385032 |
申请日期 |
2000.10.05 |
| 申请人 |
AGENSYS, INC. |
发明人 |
RAITANO, ARTHUR B.;JAKOBOVITS, AYA;AFAR, DANIEL E. H.;FARIS, MARY;HUBERT, RENE S.;MITCHELL, STEVE C.;SAFFRAN, DOUGLAS C. |
| 分类号 |
A01K67/027;A61K31/7088;A61K31/713;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61K48/00;A61P13/08;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/12;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/50;G01N33/53;G01N33/566;G01N33/577;(IPC1-7):C12N15/12 |
主分类号 |
A01K67/027 |
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