USE OF TGF BETA AND GROWTH FACTORS IN THE TREATMENT AND PREVENTION OF DISEASES OF THE INTESTINAL MUCOSA

摘要

The present invention relates to the use of transforming growth factor beta (TGF- beta ) and anabolic growth factors (AGF) in the treatment and/or prevention of malfunction or disease of the intestinal mucosa. More in particular the invention relates to the treatment and/or prevention of damage of the intestinal mucosa as a result of chemotherapy of radiotherapy or of inflammatory bowel diseases with a product comprising: a) a first pharmaceutical composition comprising TGF- beta obtained by extraction from a mammalian milk product in the substantial absence of insulin-like growth factor-1 (IGF-1); b) a second pharmaceutical composition comprising AGF in the substantial absence of TGF- beta ; wherein the first and second composition are administered sequentially.