发明名称 |
Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
摘要 |
A method for fixation of biological tissues, and bioprosthetic devices prepared by such method. The method generally comprises the steps of A) fixing the tissue, B) treating the tissue with a mixture of i) a denaturant, ii) a surfactant and iii) a crosslinking agent, C) fabricating or forming the bioprosthesis (e.g., forming the tissue and attaching any non-biological components thereto) and D) subjecting the bioprosthesis to terminal sterilization.
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申请公布号 |
US6214054(B1) |
申请公布日期 |
2001.04.10 |
申请号 |
US19980157546 |
申请日期 |
1998.09.21 |
申请人 |
EDWARDS LIFESCIENCES CORPORATION |
发明人 |
CUNANAN CRYSTAL M.;QUINTERO LILLIAN;HELMUS MICHAEL N.;LOSHBAUGH CHRISTINE;SARNER H. CHRIS;CARPENTIER ALAIN F;CARPENTIER SOPHIE |
分类号 |
A61L27/00;A61L27/36;A61L33/00;A61L33/12;(IPC1-7):A61F2/24 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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