发明名称 Process for the preparation of optically active N-benzyl-3-pyrrolidinol
摘要 The invention provides an efficient method of producing optically active N-benzyl-3-pyrrolidinol by an enzymatic reaction stereoselectively reducing N-benzyl-3-pyrrolidinone.The invention consists in a method of producing optically active N-benzyl-3-pyrrolidinol which comprises a step of obtaining a reaction mixture by treating N-benzyl-3-pyrrolidinone with cells or a culture of a microorganism, or a material derived therefrom, and a step of recovering optically active N-benzyl-3-pyrrolidinol from said reaction mixture, in which method said microorganism mentioned above is a microorganism belonging to the genus Dipodascus, Debaryomyces, Cryptococcus, Pichia, Rhodosporidium, Trichosporon, Micrococcus, Komagataella, Ogataea or Zygosaccharomyces.
申请公布号 US6214610(B1) 申请公布日期 2001.04.10
申请号 US19990308754 申请日期 1999.06.28
申请人 KANEKA CORPORATION 发明人 YASOHARA YOSHIHIKO;HASEGAWA JUNZO
分类号 C07D207/12;C12P17/10;C12P41/00;C12R1/265;C12R1/645;C12R1/84;(IPC1-7):C12D17/10 主分类号 C07D207/12
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